Interested in this as well - have a 401 sitting in the corner and keep thinking it could end up in one of my TJ's. Especially if my better half follows through and convinces me to put the stroker in her jeep.
I don't think wiring would be an issue - shouldn't need a lot of wires for a carb setup - maybe 4 or 5.
For carb I've been thinking about a Holley truck avenger.
I'm thinking the challenging part would be exhaust - not sure if anyone makes conversion headers for AMC V8 in TJ - but then I haven't started looking yet - worst case they'd be old school fenderwell.
I've collected a few tranny and Tcase options including NV4500 w/D300 and SM465 w/241 - also some AMC bellhousings to be machined to adapt the trannys.
Driveshafts - that's a given and they can be a requirement with most axle swaps anyhow.
My reasons are: 1. cuz I have it sitting around, 2. cuz it would be different, 3. cuz I like a challenge, 4. cuz I don't know when to stop, 5. cuz cuz just becuz