I can offer good input on both the Toyo MT radials, The BFG AT's, and the Goodyear Duratracs.
The Toyos (E rated) are heavier than any other radial that I know of. They also have tough sidewalls, and if you adjust you air pressure to suit the weight of the vehicle, they wear super slow and even on pavement. They are loud-ish, but deal well with mud, rocks, Moab, and gravel. If you don't mind the noise and the "nobbly bits" they are find for pavement use too - I've driven my rig all over the Western US on several road trips (one week up to one month in length) and they did great. I also find that Toyo quality control is great - the last 4 I bought didn't need any weights to balance on the factory rims.
The Duratracs (C rated), I studded and ran mostly as winter tires, although I did wheel them a bit in the fall. They offer 80% of what the Toyos do in the mud - failing mostly in the area of sliding sideways. Studded, they are very good in snow and ice - better than the BFG AT's, but that's probably partially may be due to the studs. I found them to have great manners on the road, but they are not as tough as the Toyos.