Toyos are heavy as lead-studded goose snot...but they work. On road, off road, whatever. My Toyo 35X12.5 take less weight to balance properly than my BFG 32X10.5's took. They're also uber tough if you get the e-rated ones.
I can't tell you how they handle winter roads, but I'd bet that if you siped them (or had them siped) they'd hold their own next to any MT. They won't deal with ice and snow as well as Duratracs, but they are far better than the Duratracs in the mud. I own one set of each, and I'd say that the Duratracs can only do about 80% of what the Toyos can do in mud.